Understanding your bone turnover is key to maintaining strong, healthy bones as you age. This test not only measures P1NP (a telopeptide) and CTX (a propeptide) for insights into bone formation and resorption, but also includes critical nutrients like calcium, magnesium, and phosphate that support bone structure.
Vitamin D is included in this panel to assess bone density and immune function, while PTH (Parathyroid Hormone) provides insight into calcium regulation and bone metabolism. Together, these markers help identify early signs of bone loss, monitor osteoporosis risk, and guide personalised nutrition and lifestyle strategies for optimal bone health.
This panel measures the key nutrients and hormones essential for bone health, including Parathyroid Hormone (PTH) for calcium regulation, Vitamin D for bone density, Calcium for bone strength, Phosphate for bone formation, and Magnesium for bone structure and muscle function.
PTH helps maintain stable levels of calcium in the blood and is part of a ‘feedback loop’ that includes calcium, PTH, vitamin D, phosphate and magnesium. Conditions that disrupt this feedback loop can cause inappropriate increases or decreases in calcium and PTH levels.
Although called a vitamin, vitamin D (25-OHD) is actually a steroid hormone which is activated by sunshine on the skin. It is essential for bone strength as it helps the intestines absorb calcium.
Calcium is important in building strong bones and teeth, but it also plays a key role in other functions including muscle contraction, nerve function, blood clotting, and enzyme function.
Corrected calcium adjusts for changes in serum albumin levels, providing a more accurate measure of the biologically active form of calcium, and is therefore a better reflection of the body’s calcium status.
Phosphate is a mineral which is essential for the formation of bones and teeth. It is also essential for many other cellular processes including energy metabolism and the formation of DNA and RNA.
Magnesium and calcium work together closely to maintain strong bones, and magnesium deficiency has been associated with an increased risk of osteoporosis.
P1NP is a marker of bone formation which is released during the production of collagen and reflects the rate of new bone growth. CTX on the other hand, is a marker of bone resorption, released during collagen break down and bone turnover. Together, these markers provide a comprehensive picture of bone metabolism, helping assess bone strength, monitor osteoporosis risk, and evaluate the effectiveness of bone-targeted therapies.
P1NP (Procollagen Type 1 N-Terminal Propeptide) is a protein released during the formation of type 1 collagen, the main structural protein in bone.
C-Terminal Telopeptide (CTX) is released during collagen breakdown. and high levels indicate increased bone resorption.
Fast from all food and drink (other than water) for at least 8 hours, and no more than 12 hours prior to your test.
Download and print your pathology form from your i-screen dashboard.
Take your form to one of our affiliated collection centres to have your sample taken.
